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Competitive APIs

Cyclosporin A 59865-13-3

cyclosporin a
Cyclosporin A is a cyclic undecapeptide from an extract of soil fungi. It is a powerful immunosupressant with a specific action on T-lymphocytes. It is used for the prophylaxis of graft rejection in organ and tissue transplantation. 

Cyclosporine is a natural cyclic polypeptide immunosuppressant isolated from the fungus Beauveria nivea. The exact mechanism of action of cyclosporine is not known but may involve binding to the cellular protein cytophilin, resulting in inhibition of the enzyme calcineurin. This agent appears to specifically and reversibly inhibit immunocompetent lymphocytes in the G0-or G1-phase of the cell cycle. T-lymphocytes are preferentially inhibited with T-helper cells as the primary target. Cyclosporine also inhibits lymphokine production and release. 

Cyclosporin A 59865-13-3
Appearance:white powder
Cas No:59865-13-3
Molecular Weight:1202.84
Melting Point:1293.8 °C
Boiling Point: 595 °C
Flash Point: 736.3 °C

(GMP available for Cyclosporin A) (DMF available for Cyclosporin A against commercial order quantity)(COS/EDQM/CEP passed for Cyclosporin A)
Disclaimer:Those products (Cyclosporin A / cyclosporine 59865-13-3) are for lab analytical & research purposes only.