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Antineoplastics

Streptozotocin 18883-66-4 Streptozocin

Streptozotocin 18883-66-4 Streptozocin

Streptozotocin (Streptozocin) is a naturally occurring chemical that is particularly toxic to the insulin-producing beta cells of the pancreas in mammals. It is used in medicine for treating certain cancers of the Islets of Langerhans and used in medical research to produce an animal model for hyperglycemia in a large dose as well as Type 1 diabetes with multiple low doses.

Streptozotocin is approved by the U.S. Food and Drug Administration (FDA) for treating metastatic cancer of the pancreatic islet cells. Since it carries a substantial risk of toxicity and rarely cures the cancer, its use is generally limited to patients whose cancer cannot be removed by surgery. In these patients, streptozotocin can reduce the tumor size and reduce symptoms (especially hypoglycemia due to excessive insulin secretion by insulinomas).

Streptozotocin 18883-66-4
Appearance:Pale yellow crystalline powder
Cas No:18883-66-4
EINECS:242-646-8
Formula:C8H15N3O7
Molecular Weight:265.22
Melting Point:121 °C
Boiling Point: NA
Flash Point: NA
Usage:antineoplastics

Testing Items
Standards:Enterprise
Appearance
A pale yellow crystalline powder
Identification
 
Should conform
Solubility
Soluble in water
Melting Point
121°C
Related Substances
 
 
Single Impurity:NMT0.5%
Total Impurities:NMT1.0%
Specific Rotation
+39° [α]D(C=1, H2O)
(α)-isomer
NLT75%
Residue on Ignition
NMT0.1%
Loss on Drying
NMT1.0%
Heavy metals
NMT20ppm
Assay
98.5%~101.5%

Disclaimer:Those products (Streptozotocin 18883-66-4) patented are for lab analytical & research purposes only.