Pharmaceutical & Cosmetic Raw Materials Supplier-OCTAGON CHEMICALS LIMITED

High quality CAS 1384097-27-1 or CAS 1402345-92-9,Synthetic drug GSK-F1

Product name


CAS NO. 1384097-27-1

GSK-F1; F1;5-[2-Amino-4-oxo-3-[2-(trifluoromethyl)phenyl]quinazolin-6-yl]-N-(2,4-difluorophenyl)-2-methoxypyridine-3-sulfonamide

Category Pharmaceutical Raw Materials,Active Pharmaceutical Ingredients,Bulk Drugs,Fine Chemicals.
Purity 98%+

white powder

Shelf life 2 years

GSK-F1 is a potent inhibitor of PI4KA. It has markedly better pharmacokinetic properties in vivo with respects to GSK-A1 (SYN-1219). GSK-F1 does not cross the blood-brain barrier.
Phosphatidylinositol 4-kinase type IIIα (PI4KA) is a host factor essential for hepatitis C virus replication and hence is a target for drug development. RNAi studies have shown that PI4KA is a mandatory host factor in HCV replication. Down-regulation of PI4KA appears to be reasonably tolerated by cultured cell models and results.

Storage Should be stored in a well-closed container at low temperature, keep away from moisture, heat and light.
 Note GSK-F1 for R&D use only.