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Antineoplastics

GMP Approved Vincristine Sulphate 2068-78-2

GMP Approved Vincristine Sulphate 2068-78-2

Vincristine Sulfate is a white to off–white powder. It is soluble in methanol, freely soluble in water, but only slightly soluble in 95% ethanol. In 98% ethanol, Vincristine Sulfate, USP has an ultraviolet spectrum with maxima at 221 nm (∈+47,100). 

Vincristine Sulfate is the sulphate salt of an alkaloid obtained from a common flowering herb, the
periwinkle plant (Vinca rosea Linn). Originally known as leurocristine, it has also been referred to as LCR and VCR.


Vincristine Sulfate is used to treat a number of types of cancer, including acute lymphocytic leukemia, acute myeloid leukemia, Hodgkin's disease, neuroblastoma, and small cell lung cancer.

Vincristine Sulfate was initially discovered by a team led by Dr. J.G. Armstrong, then marketed by Eli Lilly and Company. Vincristine Sulfate was extracted from leaves of the periwinkle plant, From one ton of dried leaves only one ounce of vincristine could be produced.

4 GMP Manufacturers/Holders of Vincristine Sulfate API in China: Zhejiang Hisun Pharma, Jiangsu Qinfen pharma. Guangzhou Hanfang Pharma, Hainan Periwinkle Pharma.

4 Suppliers of 
Vincristine Sulfate API with CEP: GEDEON RICHTER PLC, Eli Lilly SA, CIPLA LIMITED, MINAKEM HIGH POTENT

3 Generic suppliers of vincristine in USA: APP, Mayne, and Sicor.

Docs available of Vincristine Sulphate 2068-78-2 supplied by OCTAGONCHEM: GMP/DMF/HPLC/COA/H1NMR/MSDS