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High Purity Tofacitinib Citrate 540737-29-9 (99% as min)

High Purity Tofacitinib Citrate 540737-29-9

Tofacitinib citrate, the citrate salt of Tofacitinib, is an inhibitor of Janus kinases, a group of intracellular enzymes involved in signalling pathways that affect hematopoiesis and immune cell function.

Tofacitinib citrate is indicated for moderate to severe rheumatoid arthritis that responds inadequately to methotrexate or in those who are intolerant to methotrexate. Besides rheumatoid arthritis, tofacitinib citrate is also studied in clinical trials for the prevention of organ transplant rejection, and is currently under investigation for the treatment of psoriasis.

Tofacitinib citrate was first marketed as 5mg tablet in 2012 in USA under the name of Xeljanz by Pfizer.

Synonyms of 
Tofacitinib Citrate:

Synonyms: 1-PIPERIDINEPROPANENITRILE, 4-METHYL-3-(METHYL-7H-PYRROLO[2,3-D]PYRIMIDIN-4-YLAMINO)-BETA-OXO-, (3R,4R)-, 2-HYDROXY-1,2,3-PROPANETRICARBOXYLATE (1:1);1-Piperidinepropanenitrile, 4-Methyl-3-(Methyl-7H-pyrrolo[2,3-d]pyriMidin-4-ylaMino)-β-oxo-, (3R,4R)-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1);Tofacitinib citrate (CP-690550);Tofacitinib citrate;Tasocitinib citrate;Tasocitinib citric acid s...;Xeljanz;CP-690550 (Tofacitinib citrate)

Chemical Facts of 
Tofacitinib Citrate:
CAS: 540737-29-9
MF: C16H20N6O.C6H8O7
MW: 504.497

CEP Holder of Tofacitinib Citrate Till May 20th, 2019: None

Chinese GMP Holder for Tofacitinib Citrate Till May 20th, 2019: None

Docs Available For Tofacitinib Citrate of octagonchem: COA/HPLC/H1NMR
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